| Autor: |
Bondar, Vladimir S., Boersma, Marelle G., Berkel, Willem J.H., Finkelstein, Zoya I., Golovlev, Eugene L., Baskunov, Boris P., Vervoort, Jacques, Golovleva, Ludmila A., Rietjens, Ivonne M.C.M. |
| Zdroj: |
FEMS Microbiology Letters; December 1999, Vol. 181 Issue: 1 p73-82, 10p |
| Abstrakt: |
The regiospecificity of hydroxylation of C2‐halogenated phenols by Rhodococcus opacus1G was investigated. Oxidative defluorination at the C2 position orthowith respect to the hydroxyl moiety was preferred over hydroxylation at the non‐fluorinated C6 position for all 2‐fluorophenol compounds studied. Initial hydroxylation of 2,3,5‐trichlorophenol resulted in the exclusive formation of 3,5‐dichlorocatechol. These results indicate that, in contrast to all other phenol ortho‐hydroxylases studied so far, phenol hydroxylase from R. opacus1G is capable of catalyzing preferential oxidative defluorination but also oxidative dechlorination. |
| Databáze: |
Supplemental Index |
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