Prognostic significance of p53 expression in oral squamous cell carcinoma without neck node metastases

Autor: Carlos de Vicente, Juan, Junquera Gutiérrez, Luis Manuel, Zapatero, Agustín Herrero, Fresno Forcelledo, Manuel Florentino, Hernández‐Vallejo, Gonzalo, López Arranz, Juan Sebastián
Zdroj: Head & Neck; January 2004, Vol. 26 Issue: 1 p22-30, 9p
Abstrakt: Background.Aberrations of the p53gene and overexpression of its protein are widely recognized markers of malignancy including oral squamous cell carcinomas. This study was performed to evaluate the relationship of immunoexpression of p53 protein in series of 91 squamous cell carcinomas of the oral cavity with clinicopathologic parameters and to investigate whether p53 immunoexpression might influence the clinical outcome of the disease.
Databáze: Supplemental Index