| Autor: |
Scotté, Michel, Daveau, Maryvonne, Hiron, Martine, Ténière, Paul, Lebreton, Jean-Pierre |
| Zdroj: |
FEBS Letters; January 1993, Vol. 315 Issue: 2 p159-162, 4p |
| Abstrakt: |
The serum level of IL-6 and expression of IL-6 mRNA in hepatocytes from regenerating liver were investigated in the rat. The IL-6 level in the serum was not significantly different from that of a control group of rats submitted to an acute experimental inflammation. IL-6 mRNA expression did not occur in the liver of hepatectomized rats as judged from Northern blotting experiments using an IL-6 riboprobe. These results suggest that if IL-6 is implicated in hepatic regeneration, this cytokine is not produced by the regenerating liver and must be delivered exogenously to the liver to modulate hepatic regeneration. |
| Databáze: |
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