| Autor: |
SATO, Tadashi, FUJINO, Masayuki A., KOJIMA, Yuichiro, KITAHARA, Fumiaki, NAKAMURA, Toshiya, MOROZUMI, Atsuro, NAGATA, Kumiko, SEKIGUCHI, Tetsushi, NAKAMURA, Michihiro, HOSAKA, Hidehiro |
| Zdroj: |
Digestive Endoscopy; January 1999, Vol. 11 Issue: 1 p42-46, 5p |
| Abstrakt: |
Abstract: A variety of reliable methods are available for the detection of H. pyloriduring upper gastrointestinal endoscopy. We evaluated the clinical utility of an analyzer for H. pyloriurease composed of a solid‐phase tip coated with a monoclonal antibody against H. pyloriurease and ion‐sensitive field effect transistor‐based pH sensor system. Samples of both gastric mucus and gastric mucosal specimens were collected and the results from this system were compared. Sensitivity and specificity were 97% and 100% for mucus samples and 92% and 97% for mucosal specimens in the present system; compared to 95% and 96% for histological examination, 92% and 100% for bacteriological test, and 89% and 100% for rapid urease test, respectively. These results confirmed that the present system had high clinical sensitivity and specificity, especially for testing of mucus samples. This method has the advantage of requiring only one sample per patient because mucus can be collected from a broad area of the stomach lumen by stroking the mucosal surface with a brush. (Dig Endosc 1999; 11: 42–46) |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
Plný text