A chronic microelectrode investigation of the tonotopic organization of human auditory cortex

Autor: Howard, Matthew A., Volkov, Igor O., Abbas, Paul J., Damasio, Hanna, Ollendieck, Michael C., Granner, Mark A.
Zdroj: Brain Research; 1996, Vol. 724 Issue: 2 p260-264, 5p
Abstrakt: We investigated the functional organization of human auditory cortex using a new chronic microelectrode technique. Tonotopic mapping data was obtained at the single unit level for the first time in humans. All sound-driven units were noted to have frequency-dependent response patterns. The majority of units (73%) demonstrated sharply tuned excitatory best-frequency responses. Twenty seven percent of units showed wide receptive fields, representing excitatory responses to almost the entire range of frequencies presented. A tonotopic pattern was observed with best frequencies systematically increasing as more medial-caudal recording sites were sampled.
Databáze: Supplemental Index