Intermittent perfusion protects the brain during deep hypothermic circulatory arrest11This article has been selected for the open discussion forum on the STS Web site: http://www.sts.org/section/atsdiscussion/The Hawley H. Seiler Resident Award is presented annually to the resident with the oral presentation and manuscript deemed the best of those submitted for the competition. This Award was inaugurated in 1997 to honor Dr. Seiler for his contributions and dedicated service to the Southern Thoracic Surgical Association.

Autor:	Langley, Stephen M, Chai, Paul J, Miller, Sara E, Mault, James R, Jaggers, James J, Tsui, Steven S, Lodge, Andrew J, Lefurgey, Ann, Ungerleider, Ross M
Zdroj:	The Annals of Thoracic Surgery; July 1999, Vol. 68 Issue: 1 p4-12, 9p
Abstrakt:	Background. Deep hypothermic circulatory arrest (DHCA) has been shown to cause impairment in recovery of cerebral blood flow (CBF) and cerebral metabolism (CMRO2) proportional to the duration of the DHCA period. This effect on CMRO2may be a marker for brain injury, because CMRO2recovers normally after cardiopulmonary bypass (CPB) when DHCA is not used. The aim of this study was to investigate the effects of intermittent perfusion during DHCA on the recovery of CMRO2after CPB and to correlate these findings with electron microscopy (EM) of the cerebral microcirculatory bed.
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