Cardiac surgical conditions induced by β-blockade: Effect on myocardial fluid balance

Autor: Mehlhorn, Uwe, Allen, Steven J., Adams, Deborah L., Davis, Karen L., Gogola, Gloria R., Warters, R. David
Zdroj: The Annals of Thoracic Surgery; July 1996, Vol. 62 Issue: 1 p143-150, 8p
Abstrakt: Both crystalloid and blood cardioplegia result in cardiac dysfunction associated with myocardial edema. This edema is partially due to the lack of myocardial contraction during cardioplegia, which stops myocardial lymph flow. As an alternative, acceptable surgical conditions have been created in patients undergoing coronary artery bypass operations with esmolol-induced minimal myocardial contraction. We hypothezised that minimal myocardial contraction during circulatory support using either standard cardiopulmonary bypass (CPB) or a biventricular assist device would prevent myocardial edema by maintaining cardiac lymphatic function and thus prevent cardiac dysfunction.
Databáze: Supplemental Index