| Autor: |
Wels, B., Kruijtzer, J. A. W., Liskamp, R. M. J. |
| Zdroj: |
Organic Letters; June 2002, Vol. 4 Issue: 13 p2173-2176, 4p |
| Abstrakt: |
The solid-supported synthesis followed by cyclization in solution of cyclic (α2β)-tripeptides, potential peptide β-turn mimetics, is described. The cyclization takes advantage of facilitating the rotation between trans- and cis-rotamers of two amide bonds. The method is amenable to combinatorial approaches as is illustrated by the synthesis of a small array of cyclic (α2β)-tripeptides. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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