Inversion of the Direction of Stereoinduction in the Coupling of Chiral γ,δ-Unsaturated Fischer Carbene Complexes with o-Ethynylbenzaldehyde

Autor: Ghorai, B. K., Menon, S., Johnson, D. L., Herndon, J. W.
Zdroj: Organic Letters; June 2002, Vol. 4 Issue: 13 p2121-2124, 4p
Abstrakt: A variety of γ,δ-unsaturated carbene complexes that feature a stereogenic center at the β-carbon couple with 2-ethynylbenzaldehyde to afford hydrophenanthrene derivatives with a high degree of stereoinduction. The direction of stereoinduction is opposite for examples where the stereogenic center is acyclic vs examples where it is within a ring.
Databáze: Supplemental Index