Asymmetric Synthesis of Enantiomerically Pure Aziridinecarboxylates from N-Boc-2,2-Dimethylserinal

Autor: Jähnisch, Klaus, Tittelbach, Franz, Gründemann, Egon, Schneider, Matthias
Zdroj: European Journal of Organic Chemistry; December 2000, Vol. 2000 Issue: 23 p3957-3960, 4p
Abstrakt: Enantiomerically pure cis- and trans-aziridinecarboxylic acid derivatives 7−10 have been prepared with high syn selectivity by asymmetric Michael-type addition of benzylamine to chiral acrylates 6. The absolute configuration of (2S,3S,4R)-aziridine 10 was determined by X-ray analysis.
Databáze: Supplemental Index