| Autor: |
Ostendorf, Martin, Neut, Sandor van der, Rutjes, Floris P. J. T. |
| Zdroj: |
European Journal of Organic Chemistry; January 2000, Vol. 2000 Issue: 1 p105-113, 9p |
| Abstrakt: |
The synthesis and X-ray crystal structures of three enantiopure hydroxy-substituted amidines of the DBN-type are described. The key starting material, a 5-(phenylsulfonyl)pyrrolidin-2-one, was obtained by an oxazaborolidine-catalysed reductive desymmetrization of a meso-imide and was functionalized through N-acyliminium ion chemistry. The hydroxy groups were introduced by ozonolysis or reduction. Preliminary results on the use of the hydroxyamidines as chiral, bifunctional catalysts in selected Michael reactions are described. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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