| Autor: |
Baumgarth, Manfred, Gericke, Rolf |
| Zdroj: |
European Journal of Organic Chemistry; June 2000, Vol. 2000 Issue: 12 p2253-2255, 3p |
| Abstrakt: |
A new synthesis of the benzoylguanidine-type Na+/H+ antiporter inhibitor eniporide (7) is described. Starting from 2-bromo-5-fluorotoluene (1), aromatic substituents were introduced by methanesulfonylation, Pd-catalyzed carboxylation with CO, and halogen−pyrrole exchange. Guanidine acylation was performed using Mukaiyamas procedure. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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