| Autor: |
Goes, Marijn, Lauteslager, Xavier Y., Verhoeven, Jan W., Hofstraat, Johannes W. |
| Zdroj: |
European Journal of Organic Chemistry; November 1998, Vol. 1998 Issue: 11 p2373-2377, 5p |
| Abstrakt: |
Structural modification of the highly fluorescent donor-bridge-acceptor molecule Fluoroprobe (FP) is shown to extend the excitation window to longer wavelengths. The resulting Fluorotrope (FT) shows appreciable absorption in the 350420-nm range, so that visible (blue) light can be used for excitation. Further functionalization with a maleimide group results in the novel fluorogenic reagent MaleimidoFluorotrope (MFT) which yields fluorescent adducts with amines, thiols and other reactive groups that add to the double bond of the maleimide. The fluorescence wavelength of these adducts is extremely sensitive to the polarity and mobility of the medium. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
Plný text