Klf15Deficiency Is a Molecular Link Between Heart Failure and Aortic Aneurysm Formation

Autor: Haldar, Saptarsi M., Lu, Yuan, Jeyaraj, Darwin, Kawanami, Daiji, Cui, Yingjie, Eapen, Sam J., Hao, Caili, Li, Yan, Doughman, Yong-Qiu, Watanabe, Michiko, Shimizu, Koichi, Kuivaniemi, Helena, Sadoshima, Junichi, Margulies, Kenneth B., Cappola, Thomas P., Jain, Mukesh K.
Zdroj: Science Translational Medicine; April 2010, Vol. 2 Issue: 26 p26ra26-26ra26, 1p
Abstrakt: The co-occurrence of heart failure and aortic aneurysms may be explained by their common dependence on a transcriptional regulator, which now presents a possible therapeutic target.
Databáze: Supplemental Index