| Autor: |
Nogueira Brilhante, Raimunda Sâmia, Bezerra Fechine, Maria Auxiliadora, de Aguiar Cordeiro, Rossana, Gadelha Rocha, Marcos Fábio, Ribeiro, Joyce Fonteles, Jalles Monteiro, André, de Lima, Rita Amanda Chaves, Lima Mesquita, Jacó Ricarte, de Camargo, Zoilo Pires, Costa Sidrim, José Júlio |
| Zdroj: |
Antimicrobial Agents and Chemotherapy; September 2010, Vol. 54 Issue: 9 p3978-3979, 2p |
| Abstrakt: |
This study evaluated the in vitro effect of sulfamethoxazole-trimethoprim against Histoplasma capsulatum var. capsulatum isolated from HIV-positive patients. The drugs were tested by microdilution testing in accordance with the CLSI guidelines. All of the strains were inhibited by sulfamethoxazole-trimethoprim, with MIC ranges of 0.039 (sulfamethoxazole)/0.0078 (trimethoprim) mg/ml to 0.625/0.125 mg/ml for mycelial forms and 0.0025/0.0005 to 0.02/0.004 mg/ml for yeast-like forms. However, in vivo studies are necessary to evaluate the significance of these results. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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