| Abstrakt: |
All diastereomers of the 2-deoxypentoses and the 2,6-dideoxyhexoses were synthesized from 2-phenyl-1,3-dioxan-5-one hydrate (1), by alkylation via the RAMP-hydrazone (2). Some of the diastereomers were synthesized in the racemic form via the dimethylhydrazone (28). The 2-deoxypentoses were synthesized by alkylation with allyl bromide, followed by stereoselective reduction, ozonolysis, and deprotection. The 2,6-dideoxypentoses were synthesized by dialkylation with allyl bromide and methyl iodide. |
Plný text