Stereospecific Synthesis of Cryptophycin 1

Autor: Li, L.-H., Tius, M. A.
Zdroj: Organic Letters; May 2002, Vol. 4 Issue: 10 p1637-1640, 4p
Abstrakt: A brief stereospecific synthesis of cryptophycin 1 is described in which (R)-mandelic acid serves as the sole source of asymmetry for unit A. The key step is a hetero-Diels−Alder cycloaddition.
Databáze: Supplemental Index