Autor: |
Reddy, V. V. R. M. Krishna, Babu, K. Kishore, Ganesh, A., Srinivasulu, P., Madhusudhan, G., Mukkanti, K. |
Zdroj: |
Organic Process Research & Development; 20240101, Issue: Preprints |
Abstrakt: |
An improved, one-pot, and multikilogram-scale synthesis of 1-benzhydrylazetidin-3-ol, the pharmaceutically important moiety, has been developed. The improved process for the preparation of 1-benzhydrylazetidin-3-ol was able to minimize a content of impurities and allows the effective production of 1-benzhydrylazetidin-3-ol and its scale-up. The process was high yielding (80%) and chromatography-free with purity 99.3 area %. |
Databáze: |
Supplemental Index |
Externí odkaz: |
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