| Autor: |
Politis, I., White, J.H., Zavizion, B., Goldberg, J.J., Guo, M.R., Kindstedt, P. |
| Zdroj: |
Journal of Dairy Science; March 1995, Vol. 78 Issue: 3 p484-490, 7p |
| Abstrakt: |
The effect was examined of individual caseins on the rate of plasminogen activation by bovine urokinase-type and tissue-type plasminogen activators. All individual caseins (α-CN. β-CN, and κ-CN) enhanced the activity of both types of plasminogen activators. Optimal concentrations for α-CN and β-CN were 5 and 25μg/ml, respectively. The enhancement of enzymatic activity declined when concentrations of α-CN and β-CN were higher. In contrast, increasing concentrations of κ-CN from 0 to 200μg/ml resulted in corresponding increases in activity of both types of plasminogen activators. On a weight basis, α-CN was the most effective enhancer of plasminogen activator activity. Indirect evidence obtained with experiments utilizing α-CN immobilized on agarose suggested that the effect is related to extensive binding of plasminogen and both types of plasminogen activators to casein. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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