Autor: |
Depew, W. T., Riber, U., Depew, M. C. |
Zdroj: |
Research on Chemical Intermediates; September 1991, Vol. 16 Issue: 3 p231-239, 9p |
Abstrakt: |
Theories explaining the clinically proven efficacies of 5-aminosalicylic acid and its derivatives sulfasalazine and olsalazine in the treatment of inflammatory bowel disease have invoked the neutralization or scavenging of reactive free radicals. This is a preliminary study comparing the relative scavenging abilities of these 5-ASA derivatives towards the stable free radicals 2,2-diphenyl-1-picrylhydrazyl (DPPH) and galvinoxyl with several compounds including phenols, acetaminophen and vitamins C, K and E which have well documented antioxidant and radical scavenging capabilities both in solution and in biological systems. |
Databáze: |
Supplemental Index |
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