Onepot solvent and catalystfree synthesis of functionalized 1,8naphthyridines and quinolines by microwave irradiation

Autor: Goswami, Shyamaprosad, Jana, Subrata, Hazra, Anita, Adak, Avijit Kumar
Zdroj: Journal of Heterocyclic Chemistry; September 2007, Vol. 44 Issue: 5 p1191-1194, 4p
Abstrakt: A series of functionalized, aryl substituted naphthyridines and quinolines has been synthesized by microwaveassisted onepot twocomponent synthesis under solventfree conditions in good yields by the reaction of a variety of aryl or heteroaryl amines and aryl vinyl ketones. A combinatorial type approach for a onestep microwave reaction has been developed where a ringclosing condensation is followed by a spontaneous aromatization to afford the functionalized aryl substituted 1,8naphthyridines and quinolines.
Databáze: Supplemental Index