New efficient approach for the synthesis of 2alkylaryl substituted 4Hpyrido1,2apyrimidin4ones

Autor: Bonacorso, Helio G., Righi, Fernando J., Rodrigues, Isadora R., Cechinel, Cleber A., Costa, Michelle B., Wastowski, Arci D., Martins, Marcos A. P., Zanatta, Nilo
Zdroj: Journal of Heterocyclic Chemistry; January 2006, Vol. 43 Issue: 1 p229-233, 5p
Abstrakt: A new, efficient and easy route for the preparation of a series of 2alkylaryl substituted 4oxo4Hpyrido1,2apyrimidines, where alkyl CH3; aryl C6H5, 4FC6H4, 4ClC6H4, 4BrC6H4, 4CH3C6H4, 4OCH3C6H4, 4NO2C6H4in 45–80 yield from the reaction of βalkoxyvinyl trichloromethyl ketones with 2aminopyridine under mild conditions, is then reported.
Databáze: Supplemental Index