Synthesis of 1nonanoyloctadecanoyl4substituted thiosemicarbazides and substituted 1,2,4trizoles as biological active compounds

Autor: ColanceskaRagenovic, Katica, Dimova, Vesna, Kakurinov, Vlado, Gabor, Dora Molnar
Zdroj: Journal of Heterocyclic Chemistry; September 2003, Vol. 40 Issue: 5 p905-908, 4p
Abstrakt: 4Alkylaryl5nonanoyloctadecanoyl2,4dihydro3H1,2,4triazoline3thiones were synthesized as potential antimicrobial agents. The course of synthesis included the reaction of nonanoyloctadecanoyl hydrazines with selected alkylaryl isothiocyanates. The prepared thiosemicarbazides gave by cyclization the required 1,2,4triazoles. A number of synthesized compounds were subjected to in vitrotesting against two grampositive, two gramnegative bacteria and two fungi.
Databáze: Supplemental Index