The preparation of N1Hpyrazol3ylarylamides and 1Hpyrazol3amines from polylithiated Cα,Nthiosemicarbazones and Cα,Nsemicarbazones

Autor: Beam, Charles F., Davis, Sharon E., Cordray, Tracy L., Chan, Kam W., Kassis, Camille M., Davis, Joanna G. Freeman, Latham, G. Mark, Guion, Tina S., Hildebran, Karen C., Church, A. Cameron, Koller, Madlene U., Metz, Clyde R., Pennington, William T., Schey, Kevin L.
Zdroj: Journal of Heterocyclic Chemistry; September 1997, Vol. 34 Issue: 5 p1549-1554, 6p
Abstrakt: Cα,NThiosemicarbazones or Cα,Nsemicarbazones were polylithiated with excess lithium diisopropylamide, and the resulting cyclized intermediates were condensed with aromatic esters to afford N1Hpyrazol3ylarylamides. The polylithiated intermediates were also quenched with aqueous acid to give 5substituted, 1Hpyrazol3amines.
Databáze: Supplemental Index