Concurrent spinal cord and vertebral bone marrow radionecrosis 8 years after therapeutic irradiation

Autor: Warscotte, L., Duprez, T., Lonneux, M., Michaux, L., Renard, L., Sindic, C., Lecouvet, F.
Zdroj: Neuroradiology; March 2002, Vol. 44 Issue: 3 p245-248, 4p
Abstrakt: Concurrent radionecrosis within the spinal cord and the bone marrow at the same thoracic level was observed 8 years after localized therapeutic irradiation in a patient who had undergone repeated cycles of radiotherapy, glucocorticoid treatment, and chemotherapy for a non-Hodgkin's lymphoma. Mechanisms combining radiotoxic potentialization by glucocorticoids/alkylating agents and delayed radiation-induced vasculitis involving the common arterial pathways to the spinal cord and to the vertebrae were speculated to have acted in a synergistic way.
Databáze: Supplemental Index