| Autor: |
Li, Quan Li, Chen, Zhi Qing, Darvell, Brian W., Zeng, Quan, Li, Gang, Ou, Guo Min, Wu, Ming Yue |
| Zdroj: |
Key Engineering Materials; April 2007, Vol. 336 Issue: 1 p1699-1702, 4p |
| Abstrakt: |
A polyelectrolyte complex (PEC) composed of chitosan (CS) and phosphorylated chitosan (PCS) was used to encapsulate a calcium phosphate by a biomimetic method. An acidic CS (polycation) solution containing calcium and phosphate ions (Ca2+: 6mM, Ca/P = 1.67) was added into PCS (polyanion) solution leading to the formation of a polyelectrolyte complex (PEC) with nanoscopic carbonate-containing, low-crystallinity hydroxyapatite (HA) distributed evenly in the fibrils of the PEC by controlled crystal growth. The resulting composite material, PEC-HA, has a complicated, hierarchical porous structure that is expected to have high bio-compatibity and that may be of use as a carrier for controlled-release therapetic agents. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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