Gadolinium-Dtpa Enhancement of Vx-2 Carcinoma of the Rabbit Kidney on T1 Weighted Magnetic Resonance Images

Autor: Yancey, J. M., Ackerman, N., Kaude, Jüri V., Googe, R. E., Fitzsimmons, J. R., Scott, K. N., Mancuso, A. A., Hackett, R. L., Hager, D. A., Caballero, S.
Zdroj: Acta Radiologica; August 1987, Vol. 28 Issue: 4 p479-482, 4p
Abstrakt: Experimental renal carcinoma was induced by percutaneous injection of VX-2 carcinoma cells into the left kidney in New Zealand white rabbits. Magnetic resonance imaging (MRI) was performed at 0.15 T before and after intravenous injection of 0.3 mmol gadolinium-DTPA (Gd-DTPA) per kg body weight. Gd-DTPA enhanced the tumors by increasing the signal intensity on Tl weighted images. The enhancement was evident immediately after Gd-DTPA injection, increasing during the observation time of 30 minutes. Histologically the areas of enhancement corresponded well to the viable tumor tissue.
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