| Autor: |
Driaf, Khalid, Granet, Robert, krausz, Pierre, Kaouadji, Mourad, Verneuil, Bernard, Thomasson, François, Chulia, Albert José, Spiro, Marenglen, Biais, Jean-Claude, Bolbach, Gérard |
| Zdroj: |
Canadian Journal of Chemistry; August 1996, Vol. 74 Issue: 8 p1550-1563, 14p |
| Abstrakt: |
Trisalkylpyridinium porphyrins substituted by one glycosyl (glucosyl, maltosyl, and lactosyl) moiety have been prepared in acceptable yields. These glycosylated cationic porphyrins have been synthesized from pyrrole condensed with 4-pyridinecarboxaldehyde, and suitable ortho- or paraperacetylglycosyloxybenzaldehyde derivatives in refluxing propionic acid –Ac2O followed by action of alkyliodide in DMF. Deprotection of the glycosylated moieties led to a new class of representative glycosylated porphyrins. Keywords: porphyrins, cationic, glycosylated; phototherapy, cancer. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
