Autor: |
Yahara, Aiko, Nishida, Masaru, Baba, Takeshi, Kodama, Tetsuya, Imanishi, Takeshi, Obika, Satoshi |
Zdroj: |
Nucleic Acids Symposium Series; September 2009, Vol. 53 Issue: 1 p11-12, 2p |
Abstrakt: |
Three kinds of novel bridged nucleic acid (BNA) monomers bearing carbamate or urea bridged structures, were designed and synthesized. One of these monomers, a urea-type BNA monomer was successfully incorporated into oligodeoxynucleotides (ODNs), and properties of the ODNs were evaluated. The ODNs containing the urea-type BNA monomers showed RNA selective hybridizing profiles and significant enzymatic stability. |
Databáze: |
Supplemental Index |
Externí odkaz: |
|