| Autor: |
LIUZZI, FRANCESCA, FANELLI, CLAUDIA, CIRIOLO, MARIA ROSA, CERELLA, CLAUDIA, D'ALESSIO, MARIA, DENICOLA, MILENA, MAGRINI, ANDREA, BERGAMASCHI, ANTONIO, GHIBELLI, LINA |
| Zdroj: |
Annals of the New York Academy of Sciences; December 2003, Vol. 1010 Issue: 1 p441-445, 5p |
| Abstrakt: |
Abstract: Antioxidants‐that is, scavengers of free radicals and anaerobic conditions (5%CO2, 95% N2)‐protect monocytic U937 cells from damage‐induced apoptosis. Antioxidants rescue the cells acting on the apoptotic pathway at a step downstream from gluthatione extrusion. Reducing agents, such as DTT, also reduce stress‐induced apoptosis. Thus, apoptotic GSH extrusion triggers the downstream events of apoptosis by leaving cells unprotected against thiols oxidation and radical production. |
| Databáze: |
Supplemental Index |
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