Alcohol Actions on GABAAReceptors: From Protein Structure to Mouse Behavior

Autor: Ueno, Susumu, Harris, R. Adron, Messing, Robert O., Sanchez‐Perez, A. M., Hodge, C. W., McMahon, T., Wang, D., Mehmert, K. K., Kelley, S. P., Haywood, A., Olive, M. F., Buck, Kari J., Hood, Heather M., Blednov, Yuri, Findlay, Geoffrey, Paola Mascia, Maria
Zdroj: Alcoholism: Clinical and Experimental Research; May 2001, Vol. 25 Issue: Supplement 1 p76S-81S, 6p
Abstrakt: This article represents the proceedings of a symposium at the 2000 ISBRA Meeting in Yokohama, Japan. The chairs were R. Adron Harris and Susumu Ueno. The presentations were (1) Protein kinase Cɛ‐regulated sensitivity of γ‐aminobutyric acid type A (GABAA) receptors to allosteric agonists, by Robert O. Messing, A. M. Sanchez‐Perez, C. W. Hodge, T. McMahon, D. Wang, K. K. Mehmert, S. P. Kelley, A. Haywood, and M. F. Olive; (2) Genetic and functional analysis of a GABAAreceptor γ2 subunit variant: A candidate for quantitative trait loci involved in alcohol sensitivity and withdrawal, by Kari J. Buck and Heather M. Hood; (3) Tryptophan‐scanning mutagenesis in GABAAreceptor subunits: Channel gating and alcohol actions, by Susumu Ueno; and (4) Can a single binding site account for actions of alcohols on GABAAand glycine receptors? by R. Adron Harris, Yuri Blednov, Geoffrey Findlay, and Maria Paola Mascia.
Databáze: Supplemental Index