A stable, high relaxivity, diaqua gadolinium complex that suppresses anion and protein binding
| Autor: | Messeri, Dimitri, Lowe, Mark P., Parker, David, Botta, Mauro |
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| Zdroj: | Chemical Communications; December 21, 2001, Vol. 2001 Issue: 24 p2742-2743, 2p |
| Abstrakt: | The high relaxivity of [GdaDO3A]3− (r1p = 12.3 mM−1 s−1, 20 MHz, 298 K, τm = 30 ns) in water is maintained in serum solution because the binding of protein and endogeneous anions, e.g. HCO3−/CO32− is suppressed by electrostatic repulsion. |
| Databáze: | Supplemental Index |
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