| Autor: |
Oliveira, Gisele, Oliveira, Mariana, Santos, Raquel, Lima, Letícia, Dias, Cristina, AB' Saber, Alexandre, Teodoro, Walcy, Capelozzi, Vera, Gomes, Rachel, Bozza, Patricia, Pelosi, Paolo, Rocco, Patricia |
| Zdroj: |
Critical Care; June 2009, Vol. 13 Issue: 3 pR74-R74, 1p |
| Abstrakt: |
The protective effect of glutamine, as a pharmacological agent against lung injury, has been reported in experimental sepsis; however, its efficacy at improving oxygenation and lung mechanics, attenuating diaphragm and distal organ injury has to be better elucidated. In the present study, we tested the hypothesis that a single early intravenous dose of glutamine was associated not only with the improvement of lung morpho-function, but also the reduction of the inflammatory process and epithelial cell apoptosis in kidney, liver, and intestine villi. |
| Databáze: |
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