A Ligand Free and Room Temperature Protocol for Pd-Catalyzed Kumada−Corriu Couplings of Unactivated Alkenyl Phosphates

Autor: Gauthier, Delphine, Beckendorf, Stephan, Gøgsig, Thomas M., Lindhardt, Anders T., Skrydstrup, Troels
Zdroj: The Journal of Organic Chemistry; 20240101, Issue: Preprints p3536-3539, 4p
Abstrakt: Kumada−Corriu cross-couplings of nonactivated cyclic and acyclic vinyl phosphates with aryl magnesium reagents afforded a series of 1,1-disubtituted alkenes in good yields for most cases when the reactions were performed at room temperature with the simple palladium salt, PdCl2, without the presence of phosphine ligands.
Databáze: Supplemental Index