Utilization of thiazolylacetonitriles in the synthesis of thiophene, thiazole, pyrazolo[1,5-a]pyrimidine and pyrazolo [5,1-c]triazine derivatives

Autor: Abdelhamid, Abdou O., Zohdi, Hussein F., Mohamed, Gaber S.
Zdroj: Heteroatom Chemistry; 1999, Vol. 10 Issue: 6 p508-516, 9p
Abstrakt: Thiazolylcyanothioacetanilides react with α-haloketones and haloesters to give the corresponding thiophene or thiazole derivatives according to the reaction conditions. Pyrazolo[1,5-a]pyrimidines and pyrazolo[5,1-c]triazines were synthesized by reaction of 3-amino-4-(4'-arylthiazol-2'-yl)-5-phenylaminopyrazole with different reagents. Structures of the new compounds were confirmed by elemental analyses, spectral data, and alternative methods of synthesis whenever possible. © 1999 John Wiley & Sons, Inc. Heteroatom Chem 10: 508–516, 1999
Databáze: Supplemental Index