| Autor: |
Bushma, M., Legon'kova, L., Zverinskii, I., Khomich, T., Karpovich, V., Konovalenko, O., Karaedova, L., Lashak, L. |
| Zdroj: |
Bulletin of Experimental Biology and Medicine; February 1999, Vol. 127 Issue: 2 p176-179, 4p |
| Abstrakt: |
Abstract: An 8-day biliary obstruction in rats caused by ligation of the common bile duct is accompanied by an increase in bilirubin blood content and alanine aminotransferase activity. The hepatic xenobiotic-metabolizing activity (intensities of microsomal oxidation and glucuronidation) decreases in parallel with the inhibition of antioxidant enzymes (catalase, superoxide dismutase, and glutathione peroxidase). A comparative study of Heptral, Ursofalk, Essentiale, and Cordiamin (nikethamide) showed that Cordiamin displays the most significant enzymestabilizing activity. |
| Databáze: |
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| Externí odkaz: |
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