| Autor: |
Artmann, G.M., Kelemen, Ch., Porst, D., Büldt, G., Chien, Shu |
| Zdroj: |
Biophysical Journal; December 1998, Vol. 75 Issue: 6 p3179-3183, 5p |
| Abstrakt: |
Human red blood cells (RBC) undergo a sudden change from blocking to passing through 1.3±0.2-μm micropipettes at a transition temperature (Tc) of 36.4°C. For resealed RBC ghosts this transition occurs at 28.3°C (Tg). These findings are attributed to an elastomeric transition of hemoglobin from being gel-like to a fluid and to an elastomeric transition of membrane proteins such as spectrin. Spectrin shows a uniform distribution along the aspirated RBC tongue above Tg in contrast to the linear gradient below Tg. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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