Synthesis and Insecticidal Activity of Novel Pyrazole MethanesulfonatesBased on a paper at the meeting ‘Advances in the Chemistry of Crop Protection’ organised by P.J. Crowley, G. Mitchell, G. Keen, J. Pickett and P.D. Riordan on behalf of the SCI Pesticide Group and the RSC Biological and Medical Chemistry Group and held on 9–11 September 1996 at Churchill College, Cambridge.

Autor: Finkelstein, Bruce L., Strock, Christopher J.
Zdroj: Pesticide Science (now called Pest Management Science); August 1997, Vol. 50 Issue: 4 p324-328, 5p
Abstrakt: A model has been used to design novel pyrazole methanesulfonates. The pyrazole carboxamide methanesulfonates demonstrated insecticidal activity with low levels of acute mammalian toxicity. The amides formed from amines with α-branching (e.g. isopropyl and sec-butyl) demonstrated the highest level of activity. The model has also been used to design novel pyrazole sulfonamide methanesulfonates with very high levels of insecticidal activity. Most of the sulfonamides also possessed significant acute mammalian toxicity. Rice paddy field testing of the carboxamides on field population hoppers gave poor results. © 1997 SCI
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