| Autor: |
Beimfohr, C., Maziak, W., Mutius, E. von, Hense, H. W., Leupold, W., Hirsch, T., Keil, U., Weiland, S. K. |
| Zdroj: |
Pharmacoepidemiology and Drug Safety; June 2001, Vol. 10 Issue: 4 p315-321, 7p |
| Abstrakt: |
To describe the use of anti-asthma drugs in children in the general population and in children with asthma using data from two large surveys in Germany. Community-based random sample of 57 and 911-year-old children in Dresden and Munich were studied in 1995/96 by parental questionnaires using the Phase II protocol of the International Study of Asthma and Allergies in Childhood (ISAAC). A total of 11 094 children participated in the surveys (response rate 83%). In all children, inhaled β2-agonists were used most frequently during the last 12 months (2.6%), followed by inhaled cromolyns (2.5%), oral β2-agonists (1.5%), and inhaled steroids (0.9%). Drug use was significantly higher among boys than girls and in older children compared to younger ones (P < 0.05 for both). Among children with current asthma, 47% had used inhaled β2-agonists, 43% inhaled cromolyns, 22% oral β2-agonists, and 16% inhaled steroids. Inhaled steroids were used significantly more often in Dresden (21.7%) than in Munich (11.2%) (P < 0.05). Among anti-asthma drugs, agents used for symptomatic relief were the most frequently reported followed by inhaled anti-inflammatory agents. Most of the anti-inflammatory drugs used were SCG, which may indicate under-treatment with inhaled steroids. Copyright © 2001 John Wiley & Sons, Ltd. |
| Databáze: |
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