| Autor: |
Smets, K., Roets, E., Miller, J., Porqueras, E., Berti, N., Vettori, P., Folliard, F., Hoogmartens, J. |
| Zdroj: |
Chromatographia; December 1993, Vol. 37 p640-644, 5p |
| Abstrakt: |
An established method for the analysis of chlortetracycline by liquid chromatography using octylsilylated silica gel as the stationary phase was examined in a multicentre study involving five laboratories and a total of six columns. Three chlortetracycline hydrochloride samples were analysed. The main component and the impurities were determined. An analysis of variance, treating each column as a different laboratory, showed an absence of consistent between-laboratory bias and the presence of a significant laboratory-sample interaction. The repeatability and the reproducibility of the method, expressed as relative standard deviations of the result of the determination of chlortetracycline hydrochloride, were calculated to be 0.9% and 1.1% respectively. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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