| Autor: |
Winkelspecht, B., Grässer, F., Pees, H. W., Mueller-Lantzsch, N. |
| Zdroj: |
Archives of Virology; May 1996, Vol. 141 Issue: 5 p857-864, 8p |
| Abstrakt: |
Summary Reactivation of EBV infection is common in immunocompromised individuals. We determined specific antibodies to EBV-encoded nuclear antigens (EBNA) 1 and 2 in 102 sera of HIV-infected individuals. Anti-EBNA1/anti-EBNA2 ratio (E1/E2) is less than 1 in chronic infection and exceeds 1 in healthy EBV-positive carriers. 52% of cases had E1/E2<1. E1/E2 decreased remarkably during the progression of HIV infection. Detectable HIV-Antigen, decline of CD4 + cell count and CD4 + /CD8 + ratio were correlated with an increasing prevalence of E1/E2 below 1. We conclude that determination of E1/E2 is useful in immunocompromised patients. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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