| Autor: |
Adolf, G. R., Haas, O. A., Fischer, P., Swetly, P. |
| Zdroj: |
Archives of Virology; September 1982, Vol. 72 Issue: 3 p169-178, 10p |
| Abstrakt: |
Summary A large number of human haematopoietic cell lines was examined for spontaneous production of interferon. Unconcentrated culture supernatants from 70 out of 71 B-lymphoblastoid cell lines contained considerable amounts of interferon (median titer 22 units per ml); a few lines produced more than 100 units/ml with peak values up to 500 units/ml. In contrast, only one B-lymphoma line out of 18 genuine lymphoma, myeloma, and leukaemia cell lines tested spontaneously produced small amounts of interferon. Following treatment with 5-bromodeoxyuridine (BrdUrd), interferon was produced without further induction in most B-lymphoid cell lines, but not in any of the non-B, non-T, T-lymphoid or myeloid lines examined. |
| Databáze: |
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| Externí odkaz: |
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