Action of Histone on Reproduction of vaccinia virus

Autor: Balandin, I. G., Melnikova, L. A., Kozlova, I. A., Peterson, O. P., Masharina, L. V., Zhdanov, V. M.
Zdroj: Archives of Virology; September 1966, Vol. 18 Issue: 3 p350-355, 6p
Abstrakt: Histone isolated from calf thymus inhibits the reproduction of DNA-containing vaccinia virus. F1and F3fractions of histone have the same effect though in a lesser degree than crude histone. F1fraction has a stronger inhibitory effect than the F3fraction. Inhibitory action of histone on the reproduction of vaccinia virus is principally attributed to the formation of a complex of the viral DNA with histone.
Databáze: Supplemental Index