Recent advances in immunologic diagnosis of digestive tract cancer

Autor: Stillman, Alfred, Zamcheck, Norman
Zdroj: Digestive Diseases and Sciences; November 1970, Vol. 15 Issue: 11 p1003-1018, 16p
Abstrakt: Recently, several immunologic tests for the detection of gastrointestinal malignancy have been described. These tests operate on the principle that malignant tumors may contain antigens that are not present in nonmalignant tissues or that are present in these tissues in either insignificant amounts or undetectable forms. The tumor-associated antigens may be largely specific (with exceptions) for a given organ such as the liver (hepatoma), as in the case ofα-fetoglobulin, or for an organ system such as the gastrointestinal tract, as in the case of carcinoembryonic antigen. Several of these antigens have been found in various fetal tissues, thereby establishing a link between fetal biology and tumor pathogenesis.
Databáze: Supplemental Index