| Autor: |
Gerber, Marietta J., Phuangsab, Anan, Vittal, Sudin B. V., Dourdourekas, Demetrios, Steigmann, Frederick, Clowdus, Bernard F. |
| Zdroj: |
Digestive Diseases and Sciences; July 1974, Vol. 19 Issue: 7 p637-643, 7p |
| Abstrakt: |
Cell-mediated immune response (CMIR) to both serum and purified hepatitis B antigen (HBAg) was measured in 151 subjects using the leukocyte MIF test. Ninety-five percent of patients with HBAg-positive acute viral hepatitis (AVH) and 64% of patients with HBAg-negative AVH had positive MIF tests. Positive MIF tests were rarely present in asymptomatic HBAg carriers and were not found in patients with alcoholic liver disease or in normal controls. The data suggest that many patients with AVH in whom HBAg is undetectable may have hepatitis B and that measurement ofin vitro MIF to HBAg is a sensitive index for establishing the etiological role of the antigen in the liver disease. |
| Databáze: |
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