| Autor: |
Yakhontov, L. N., Suvorov, N. N., Kanterov, V. Ya., Podkhalyuzina, N. Ya., Pronina, E. V., Starostenko, N. E., Shkil'kova, V. N. |
| Zdroj: |
Chemistry of Heterocyclic Compounds; May 1972, Vol. 8 Issue: 5 p594-596, 3p |
| Abstrakt: |
The catalytic synthesis of 7-azaindole and its 2-methyl derivative has been accomplished for the first time by cyclization of acetaldehyde and acetone 2-pyridylhydrazones in the presence of ?-Al2O3 and fluorinated aluminum oxide. The temperature dependence of the yields of reaction products — azaindoles and 2-aminopyridine — was studied. The cyclization of acetaldehyde 2-pyridylhydrazone proceeds under more severe conditions. The maximum yield of 7-azaindole is 15% at 450° on fluorinated aluminum oxide. The yield of 2-methyl-7-azaindole reaches 50% at 315°. Fluorinated aluminum oxide displays higher catalytic activity. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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