Bromination of 2,6-dimethyl-3,5-dimethoxycarbonyl-4-(2′-difluoromethoxyphenyl)-1,4-dihydropyridine (foridone)

Autor: Skarstin'sh, I. P., Kastron, V. V., Dubur, G. Ya., Mazheika, I. B., Liepin'sh, É. É.
Zdroj: Chemistry of Heterocyclic Compounds; July 1989, Vol. 25 Issue: 7 p791-795, 5p
Abstrakt: The action of mild brominating agents (pyridinium bromide-perbromide, dioxan dibromide N-bromosuccinimide, and N-bromoacetamide) on 2,6-dimethyl-3,5-dimethoxy-carbonyl-4-(2'-difluoromethoxyphenyl)-1,4-dihydropyridine (Foridone) has been studied. Depending on reaction conditions, furo-, difuro-, and dibromomethyl-1,4-dihydropyridines are obtained together with certain oxidized forms.
Databáze: Supplemental Index
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