(HET) Arylation of substituted acetonitriles. 1. Synthesis of 2-amino-3-(benzimidazol-2-yl)pyrrolo [2,3,b]-quinoxalines

Autor: Kozynchenko, A. P., Volovenko, Yu. M., Promonenkov, V. K., Turov, A. V., Babichev, F. S.
Zdroj: Chemistry of Heterocyclic Compounds; August 1988, Vol. 24 Issue: 8 p923-927, 5p
Abstrakt: It was shown that hetarylation of benzimidazol-2-ylacetonitriles by 2,3-dichloro-quinoxaline proceeds at the methylene group. The reaction of 2-chloro-3-[a-cyano-a-(benzimidazol-2-yl) methylene]-3,4-dihydroquinoxalines formed with primary amines leads to 1-R-2-amino-3-(benzimidazol-2-yl)pyrrolo [2,3-b] quinoxalines.
Databáze: Supplemental Index