6,7,8,9-Tetrahydrodipyrimido[4,5-b][4′,5′-e][1,4]thiazine derivatives. Synthesis and structure

Autor: Nemeryuk, M. P., Traven', N. I., Arutyunyan, T. G., Shatukhina, E. A., Nerseyan, N. A., Anisimova, O. S., Solov'eva, N. P., Peresleni, E. M., Sheinker, Yu. N., Sokol, O. G., Kazakova, V. M., Safonova, T. S.
Zdroj: Chemistry of Heterocyclic Compounds; February 1989, Vol. 25 Issue: 2 p214-220, 7p
Abstrakt: The reaction of 5-amino-6-mercaptopyrimidines with 1,3-dimethyl-5-nitro-6-chlorouiracil in the presence of bases results in derivatives of 6,7,8,9-tetrahydrodipyrimido[4,5-b][4',5'-e][1,4]-thiazine. If the 5-amino-6-mercaptopyrimdine contains a free or alkyl-substituted amino group at the 4-position, the tetrahydrodipyramidothiazines formed exist in a free radical form. The structure of the compounds formed has been established by spectral methods.
Databáze: Supplemental Index