synthesis of γ-monolactones of 2,7-dialkyl-2,7-diamino-4-hydroxyoctane-1,8-dioic acids and their 4-methyl-substituted derivatives

Autor: Manukyan, M. A., Akhnazaryan, A. A., Asikyan, S. M., Dangyan, M. T.
Zdroj: Chemistry of Heterocyclic Compounds; April 1977, Vol. 13 Issue: 4 p360-362, 3p
Abstrakt: γ-Monolactones of 2,7-dialkyl-2,7-diamino-4-hydroxyoctane-1,8-dioic acids and their 4-methyl-substituted derivatives were synthesized by the Gabriel reaction from the appropriate α, α′-dichlorolactone esters, which are formed by cyclization (catalytically with H2SO4 or thermally) of 2,7-dialkyl-2,7-dichloro-4-octene-1,8-dioic acids or their 4-methyl-substituted derivatives and subsequent esterification of the acid grouping.
Databáze: Supplemental Index
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